Cytokeratin 1 anticorps (pan)

N° du produit ABIN452372

L’anticorps Souris Monoclonal anti-Cytokeratin 1 a été validé pour IHC (p), IF et IHC (fro). Il convient pour détecter Cytokeratin 1 dans des échantillons de Humain, Rat, Boeuf (Vache), Poulet, Serpent, Xenopus laevis et Pleurodeles.

Aperçu rapide pour Cytokeratin 1 anticorps (pan) (ABIN452372)

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivité: Humain, Rat, Boeuf (Vache), Poulet, Serpent, Xenopus laevis, Pleurodeles

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: Lu-5

Détail du produit anti-Cytokeratin 1 anticorps

Épitope: pan

Specificité: This antibody reacts to Cytoketatin pan.

Attributs du produit: Synonyms: pan Keratin, Cytokeratin Pan-reactive

Purification: Ion exchange chromatography

Immunogène: Cells of lung cancer cell line A549 and A2182.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on frozen and paraffin sections: 1/20.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in 1 mL dist. water

Buffer: 0.09 % sodium azide, 0.5 % BSA in PBS buffer, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Cytokeratin 1

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Autre désignation: Cytokeratin

Sujet: Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.Synonyms: Cytokeratin pan-reactive, pan Keratin